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Cute But Dumb (CBD) vs. Turkey Ham & Cheese (THC)?

CBD (Cannabidiol) vs THC (Tetrahydrocannabinol)

What is CBD? How is it different from marijuana?

CBD is cannabidiol, one of the active ingredients of marijuana and hemp plants (Cannabis). 
  • Hemp is the name given to classify types of cannabis that contain 0.3% or less of THC
  • Marijuana is the name given to classify types of cannabis that contain more than 0.3% THC
CBD does not produce a “high.”

What is THC?

THC is the main active ingredient in marijuana plants that produces a “high.”
Hemp and marijuana can often appear indistinguishable from one another as they are varieties of the same plant species.

Is CBD Legal?

The Farm Bill of December 2018 legalized CBD derived from hemp that contains no more than 0.3% THC. CBD products are legal at the federal level, however, local state governments still have the final say on how exactly these products can be cultivated, manufactured, and purchased within their state lines. 
Laws regarding CBD and cannabis can change quickly, as we’ve seen in recent years with the rapidly increasing popularity of CBD. Check with your state’s government website to see if any changes have occurred.


Why is it important?

According to initial results from Ryan Vandrey, associate professor of psychiatry and behavioral sciences at Johns Hopkins,
“We found that, among individuals with various health problems including epilepsy, chronic pain, autism, anxiety and other serious health conditions, those who were using a cannabis product — people predominantly used CBD products — reported a better quality of life and satisfaction with health, pain, sleep and mood compared with those who were not using cannabis products.”
Dr. Peter Grinspoon published in the Harvard Health Blog,
“CBD has been touted for many health issues, but the strongest scientific evidence is for its effectiveness in treating some of the cruelest childhood epilepsy syndromes, including Dravet syndrome and Lennox-Gastaut syndrome (LGS), which typically don’t respond to antiseizure medications. In many studies, CBD could reduce the number of seizures, and in some cases it could stop them altogether.”
While present day research only supports treatment with prescription grade CBD for rare childhood epilepsy syndromes, the movement toward exploring the therapeutic value of CBD has many wondering about other possible benefits.

Is CBD safe?

Many report no side effects. As with all products, some people may experience side effects or reactions. Side effects of CBD can include nausea, fatigue, and irritability.
In addition, patients taking blood thinners like warfarin (coumadin) and other medications can have increased drug levels in the blood.
At certain doses, CBD can temporarily deactivate cytochrome P450 enzymes. This changes how certain prescription drugs are metabolized.
Patients with liver insufficiency should consult their doctor.
CBD during pregnancy and breastfeeding hasn’t been thoroughly researched.
Always consult your doctor before taking any new product.

For you biochem nerds out there, CBD is a potent inhibitor of CYP3A4 and CYP2D6 enzymes. CBD is metabolized, among others, via the CYP3A4 enzyme. CYP3A4 inhibitors (ketoconazole, itraconazole, ritonavir, and clarithromycin) lead to slower CBD degradation and can consequently lead to higher CBD doses that are longer pharmaceutically active. In contrast, phenobarbital, rifampicin, carbamazepine, and phenytoin induce CYP3A4, causing reduced CBD bioavailability. Approximately 60% of clinically prescribed drugs are metabolized via CYP3A4. Studies in mice have shown that CBD inactivates cytochrome P450 isozymes in the short term, but can induce them after repeated administration. 

What is CBD?

Even though THC and other cannabinoids act right on the cannabinoid receptors at the ECS, Cannabidiol includes a slightly different character. While we’re unable to produce medical claims in relation to Cannabidiol and CBD goods, we strongly advise doing additional research into the benefits of this wonderful cannabinoid. In animals such as puppies, as a portion of their central nervous system and the peripheral system, endocannabinoids are composed of lipids. They’re neurotransmitters, which means they transfer compounds to and round the mind of the dogs.
How Can CBD Work? The cannabis plant includes 113 active chemicals known as cannabinoids. CBD, brief for Cannabidiol, is just one of these. In addition, it appears to be the next cannabinoid — alongside THC — which happens in prosperity. At times, but the ECS can not catch up with all the damage, which may be the reason behind serious chronic conditions, according to some investigators. In any case, CBD works on 60 distinct molecular pathways, affecting nitric oxide, immune system, vanilloid receptors, and much more. It is a flexible compound and the amount of health-conscious consumers using it on a regular basis is a living evidence of this. The endocannabinoid system controls a broad array of biological functions, such as mood, sleep, temperature controller, immune reaction, pain and delight understanding, fertility, memory, and desire. Whenever something wrong occurs with your wellbeing, the endocannabinoid system will discharge its natural cannabinoids (endocannabinoids) to reestablish the balance and deliver you up and around. CBD is a remarkably intricate cannabinoid and its own interaction with an endocannabinoid system has to be deeply researched to show its entire potential. Happily, as scientists are planning to dive all-in to research on cannabinoids, it is merely a matter of time before CBD makes it into the mainstream on an international scale. In addition to this, CBD includes a plethora of health benefits, and although hemp-derived CBD is categorized as a nutritional supplement, there are legions of those who have enhanced the quality of the life with the easy usage of Cannabidiol. Unlike THC, CBD doesn’t have intoxicating properties, therefore it will not cause you to feel”high” Even better, CBD was clinically demonstrated to offset the damaging effects of THC, such as elevated stress brought on by overconsumption of the chemical.
Like we mentioned, CBD does not interact directly with cannabinoid receptors (CB1 and CB2), but alternatively, it arouses the endocannabinoid system to create its own cannabinoids. Additionally, it slows their breakdown by inhibiting the FAAH enzyme, therefore the endocannabinoids can remain in the body for more. From the 1980s, President Ronald Reagan drove tens of thousands of millions of bucks into studies which were aimed to demonstrate that marijuana causes brain damage and cognitive impairment. As you may suspect, these studies failed to establish the biased assert and instead, they ended up discovering the endocannabinoid system. The endocannabinoid system is a intricate system of mobile receptors and receptors which are responsible for maintaining homeostasis within the body. Cannabinoid receptors have been dispersed across the whole body, with biggest concentrations in the peripheral and central nervous systems, also from the immune system. The ECS enhances the communication between those systems. There’s various research about the effects of CBD for puppies so that you will feel comfortable about providing CBD and hemp goods to your very best buddies.