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What Everybody Needs To Know About Taking CBD With THC

When it comes to cannabis — you’re either consuming THC or CBD.

However, why not use them at the same time?

From short-term pain relief to long-lasting anxiety support, consuming THC and CBD simultaneously is a beneficial method to get the most from your cannabis-based products.

Read along and learn how you can use CBD and THC together. You’ll discover everything you need to know, such as the advantages and disadvantages of combining THC and CBD for the ultimate cannabis experience.

What is THC?

First, let’s briefly discuss THC.

Tetrahydrocannabinol, widely known as THC, is a psychoactive cannabinoid found in abundance in THC-rich cannabis. Overall, THC is known for a multitude of beneficial effects.

However, THC is known to produce strong mental and physical sensations. Ultimately, THC provides medical patients and recreational enthusiasts with a form of rapid relief that may last upwards of 1-4-hours.

What is CBD?

Next, let’s touch upon CBD.

CBD, also known as cannabidiol, is a non-psychoactive cannabinoid that’s dominant in hemp-derived plants. Although hemp is cannabis, it is a subspecies that naturally contains negligible levels of THC.

As previously noted, consuming CBD will not get you high. Instead, CBD produces background effects that promote wellness in the mind and body.

Overall, CBD must be taken over time to elicit beneficial effects, such as reduced anxiety or decreased pain.

Is There CBD in My Cannabis?

If you’re using medical or recreational cannabis from a dispensary — it’s unlikely that it has noticeable amounts of CBD unless specified.

Luckily, lab-testing has become routine among reputable cannabis producers, which allows you to check the verified cannabinoid levels in each product. As you review the lab results, don’t be surprised to find sky-high THC levels and low amounts of CBD.

Alternatively, hemp-derived CBD products are practically void of THC. Therefore, where’s the middle ground considering THC and CBD provide a plethora of beneficial effects?

Let’s take a look at the advantages and disadvantages of using THC and CBD together.

The Benefits of Using THC and CBD Together

Now, let’s discuss the benefits of using THC and CBD together.

You might ask — why should I use THC and CBD together if there’s already CBD in my weed?

A reasonable question deserves a proper answer: there isn’t nearly enough CBD in traditional cannabis products. For example, a THC-rich cannabis strain may provide upwards of 24% THC and 1% CBD. As you can see, there isn’t a balance that allows you to benefit from both cannabinoids.

Now that you understand why you would use CBD in conjunction with THC-rich products let’s outline the benefits of using these incredible cannabinoids together.

Reduce THC’s Psychoactive Effects and Get Work Done

Have you ever smoked weed while trying to study or get chores done?

We’ve all been there, and the result is typically the same — we find ourselves lost in the sauce of our stoned thoughts.

Although the psychoactive effects of THC-rich cannabis are undeniably enjoyable, sometimes you need to get stuff done. Luckily for you, CBD tempers THC’s psychoactive effects because it’s an allosteric modulator.

Therefore, if you consume THC and CBD products together, you will experience the benefits they both have to offer, all while reducing the intense psychoactive effects of consuming THC.

You must wonder — how does CBD reduce the psychoactive effects of THC?

As you consume CBD, cannabidiol blocks CB1 receptors and THC from making contact. By doing so, CB1 receptors deactivate and restrict THC molecules from making a bond.

Therefore, consuming THC and CBD-based cannabis products together creates a less psychoactive experience while enabling users to reap the therapeutic and recreational benefits that cannabinoids have to offer.

The Entourage Effect

When it comes to cannabis — it’s always beneficial to consume a variety of cannabinoids.

The entourage effect describes the beneficial experience that results from consuming more than one cannabinoid. THC, along with CBD, offers users a myriad of benefits. However, studies show that THC and CBD complement each other.

Consuming THC or CBD isolate is not the ideal route to combat these mental and physical issues. Instead, consuming THC and CBD-based cannabis products may amplify the entourage effect for effective results.

Take THC’s Edge Off

Sometimes, THC-rich cannabis produces bouts of anxiety.

Whether you smoked too much or life threw a curveball, you may feel anxiety after consuming THC-rich marijuana.

By using CBD, you can off-set any anxious feelings that may otherwise ruin your overall experience.

CBD is known to drastically reduce anxiety via multiple pathways, such as serotonin signaling, TRPV1 proteins, and PPARs.

Let’s take a look at each detail to understand better how CBD reduces THC’s potentially anxious effects.

Serotonin Signaling

There’s a reason why serotonin is known as the happy drug.

Serotonin is a natural hormone produced by the body and stabilizes mood, sleep, eating habits, and even digestion. However, serotonin is most well-known for its natural ability to boost your level of happiness.

If a THC-induced experience begins to spiral out of control, serotonin may play a leading role in reducing anxious feelings. However, how can you produce serotonin with CBD?

By combining CBD with THC-based products, the CBD molecule directly signals the 5-HT1A receptor group responsible for serotonin production.

TRPV1 Protein

CBD is surprisingly versatile and interacts with various proteins and receptors outside of the CB2 receptor group.

The TRPV1 protein, also known as the transient receptor potential vanilloid, is a compound that produces anxiolytic (anti-anxiety) effects. Furthermore, TRPV1 proteins interact directly with the CB1 receptor group, which may provide additional support against stressors that result in anxiety.


PPARs, also known as peroxisome proliferator-activated receptor-γ, promote a myriad of benefits throughout the body.

In regards to anxiety, however, it interacts directly with CBD to produce anxiolytic effects. Unlike CBD, THC is unable to activate PPARs to a noticeable level, which adds to why you would consume THC and CBD products together.

The Yin and Yang of The Endocannabinoid System

Whether you’re new to cannabis or not — you must understand what the endocannabinoid system is.

The endocannabinoid system, ECS for short, is a biological system composed of endocannabinoids and neurotransmitters. As it so happens, cannabis contains cannabinoids that bind directly with cannabinoid receptors — CB1 and CB2.

Although the CB1 and CB2 receptor groups exist within the overall endocannabinoid system — they are primarily activated by specific cannabinoids. Furthermore, the CB1 and CB2 receptor groups are found in different body locations, and therefore, promote different effects.

Let’s take a look at each for a better understanding of the benefits of using both THC and CBD products simultaneously.

The CB1 Receptor Group

The CB1 receptor group is located within the brain’s nerve cells, spinal cord, and peripheral organs. Furthermore, CB1 receptors are also found in the spleen, white blood cells, and endocrine glands.

As you can see, CB1 receptors are located in significant portions of the body that are responsible for day-to-day living.

As it so happens, THC is primarily associated with interacting with the CB1 receptor group.

The most significant interaction between THC and CB1 receptors occurs in the brain. When an individual consumes THC, the THC molecule binds to the CB1 receptor located in the brain.

The psychoactive effects are nearly instant, such as:

  • Loss of emotional control
  • Reduced motor skills
  • Decreased awareness of time
  • Heightened senses

As you can see, the effects may seem one-sided. By consuming THC-rich cannabis, you are only activating one of two endocannabinoid receptors.

However, the story changes once you add CBD and the CB2 receptor group to the equation.

The CB2 Receptor Group

The CB2 receptor group is located in white blood cells, the spleen, and even your tonsils. Furthermore, the CB2 group is also found in immune cells, which are the immune system’s foundation.

Cannabidiol is known to, directly and indirectly, interact with the CB2 receptor group. Due to this interaction, CB2 receptors are believed to bolster the immune response, reduce anxiety, and decrease inflammation.

Unlike THC, CB2 receptor modulation produces effects that promote wellbeing in the form of:

  • Reduced anxiety and depression
  • Decreased pain and inflammation
  • Appetite regulation
  • Stimulate the immune response

Therefore, THC and the CB1 receptor group provide the yin to CBD and the CB2 group’s yang. In other words, the CB1 and CB2 receptor groups are complimentary, interconnected, and interdependent on each other.

Ultimately, consuming THC and CBD provide ample benefits that are best experienced when used together.

The Disadvantages of Using THC and CBD Together

Now that you understand the benefits of using THC and CBD together let’s discuss the disadvantages.

Although it may seem counterintuitive, there are a few disadvantages to speak of when using THC and CBD together.

Two Cannabis Products Are More Expensive Than One

When it comes to disadvantages, nothing is more glaring than the cost of cannabis-based products. Let’s face it — not all of us can afford two cannabis products at once.

Whether you purchase a gram of THC-rich flower or shatter — it might dent your wallet. Now, add an additional CBD product to the mix, and now we’re talking about a lot of money.

In other words, you’ll need to buy two products to enjoy the benefits associated with consuming THC and CBD together.

Therefore, you may find yourself footing a large bill to experience the psychoactive effects of THC and the therapeutic qualities of CBD.

You Want To Get High

There’s no shame in saying that all you want is to get stoned.

Recreational marijuana exists for this very reason, and if you live in a recreational state — you’re in luck.

However, you don’t want to combine THC and CBD-based cannabis if you want to reach cloud nine. As you may remember, CBD acts as an allosteric modulator, which significantly decreases the psychoactive effects of THC.

Therefore, find a high THC cannabis product that’s void of CBD for optimal results.

You Are Getting Drug Tested

Although cannabis legalization is just around the corner — some workplaces still drug test employees.

As you may know, THC is a prime target for drug tests, and if you test positive — you may lose your job. Therefore, it’s best to leave the THC-rich cannabis alone when applying for a new job.

Instead, use a CBD-rich cannabis product that doesn’t contain any THC or, at least, negligible levels of THC.

CBD reduces the effects of THC

You Don’t Want To Feel High

Alternatively, some people don’t want to feel high.

Whether THC-rich cannabis promotes anxiety or you need to stay focused — it’s not advantageous to consume THC and CBD together.

Although CBD is an allosteric modulator and reduces the effects of THC, you may still experience psychoactive effects. Therefore, it’s best to consume CBD isolate or broad-spectrum CBD products that are void of THC.

You Need Specific Medical Benefits

Another disadvantage of consuming THC and CBD together is if you want specific medicinal benefits from CBD.

Although we can argue in favor of the entourage effect, there is evidence that consuming CBD isolates may assist individuals with specific issues.

The Choice is Yours

Ultimately — it’s your choice to use CBD and THC together.

Depending on your situation, each of these cannabinoids may prove useful together or separate. Therefore, it’s for you to decide whether or not to consume THC and CBD products together.

From the recreational effects of THC-dominant cannabis and the medicinal potential of hemp-derived CBD — both cannabinoids provide incredible benefits that millions of cannabis enthusiasts enjoy daily.